We build microfluidic and engineering tools to enable high throughput analysis of cells. We design new droplet microfluidic devices and assemble into workflows for systems biology studies.
We develop molecular methods for profiling cellular interactions. Current projects are focused on genome-wide CRISPR screens and in vivo reconstruction of glial networks with viral tracing.
A major interest of the lab is understanding HIV latency in CD4 T cells. We are applying new droplet microfluidic sorting techniques to study the transcriptional profiles of infected cells ex vivo.